Cosmetics and perfumes are an integral part of some people’s lives, while some are allergic to these beauty products. Have you ever thought about what could be liable for this sensitiveness to fragrances? Maybe, people are allergic to particular compounds present in cosmetics. But what exactly causes these reactions? Well, it is nothing but a protein. Now researchers have found a specific protein that initiates responses when a person gets in touch with essences commonly present in cosmetic products. The protein can propel immune cells into overwork condition when people use everyday cosmetics. The range includes products like soaps, toothpaste, body washes, shampoos, and even lotions.
Before, this it had remained mysterious, what and how it triggers allergic reactions. Researches from Monash University, the Brigham and Women’s Hospital, Columbia University Irving Medical Center have unveiled the secret behind allergies. A new study, published in journal Science Immunology, recommends a new approach to treat the condition. Also, it proposes the way several chemical change natural fats present in skin cells, which in turn reveals the number of common elements initiate allergies. Apart from this, the discovery could assist in reducing increasing instances of blisters, rashes, itchy eyes, lumps, etc. The researchers have named the connection as “molecular missing link”.
As per the research, CD1a is a key protein present in immune cells that create the external layer of our skin. Experiments have revealed that the element has a direct link with irritants or allergens present in toiletries by triggering the T cells of the immune system. T cells are white blood cells that attack and kill foreign intruders in the body. Allergies arise when T cells mistake the identity of some compounds. They even start responding to harmless substances. Prof. David Moody, the study’s co-senior author, said chemicals present in cosmetics, including skin creams, could trigger allergic contact dermatitis (ACD).
The study reveals the response of T cells to some elements, including Peru’s balsam. Even more, the researchers have further recognized constituents of tree oil benzyl cinnamate and benzyl benzoate. The team has found both ingredients liable for stirring the reaction. The team has analyzed similar elements and has discovered around 12 molecules that seem to provoke a response. The study also focuses on farnesol, a type of alcohol various products like shampoos, shower gels, anti-aging creams, and deodorants. Now the scientists aim to whether allergic people commonly have T cells that determine molecules like farsenol. They are also looking for new components that could stop CD1a from responding.